Second International
BioArrays-2004-New York Meeting
“Biochips in Diagnostics, Industrial Genomics &
Proteomics: Systemomics™ Approaches”
At Holiday Inn Midtown, 440 West 57th Street,
New York City, New York, USA
(Few Blocks from Central Park and Times Square)
On
July 26-27, 2004
|
Target Audience: |
300 |
| Total
Speaker Presentations: |
30 |
| Total
Poster Presentations: |
30 |
| Total
Exhibit Booths: |
30 |
AGENDA/SPEAKERS
Click
Here for the Final Agenda(.pdf)
Monday,
July 26, 2004
7.00 A.M: Registration Open
7.30 –
9.00 A.M: Continental Breakfast
Technology Session I (consists of 3 lectures)
Scientific Sessions Start at 9.15 A.M and ends at 5.45 P.M.
Tuesday,
July 27, 2004
7.30 – 9.00 A.M: Continental Breakfast
Technology Session II (consists of 3 lectures)
Scientific
Sessions Start at 9.15 A.M and ends at 5.45 P.M.
The
actual agenda will be updated. Please visit again.
Scientific
Advisory Committee:
- K. Appasani, PhD., MBA.
GeneExpression
Systems, Inc.
- J. Ju, PhD. Associate Professor, Columbia University
College of Physicians & Surgeons
- J. L. Walewski,
PhD. Assistant Professor, Mount Sinai School of
Medicine, NYU
- J. LaBaer, MD,PhD. Harvard Institute
of Proteomics, Harvard Medical School
Inaugural
Speaker:
Eric
Kandel, MD.
Nobel Laureate 2000 (Medicine & Physiology)
Columbia University College of Physicians & Surgeons
New York, NY
Keynote
Speaker:
John
Burczak, PhD.
Vice President of Development
GE HealthCare (Formerly Amersham Biosciences)
Piscataway, NJ
Key
Presentations: (Will be updated from time-to-time)
Legionella pneumophila: From genome to transcriptome
James J. Russo, Ph.D. Research Scientist and Associate Head
Sequencing and Chemical Biology, Columbia Genome Center,
Columbia University, New York, NY
Zooming In: Moving from
Genome-Wide Expression Profiling to High-Throughput Fingerprint
Screening
Jay P. Tiesman, Ph.D. Genomics Group Leader, Procter &
Gamble, Cincinnati, OH
Noninvasive diagnosis of liver cirrhosis using DNA-sequencer-based
total serum protein glycomics
Roland Contreras, PhD. Professor of Molecular Biology, Ghent
University, Belgium
Application of Gene
Expression Profiling to drug discovery in Regeneron Pharmaceuticals
Yi Wei, Ph.D. Regeneron Pharmaceuticals, Inc. Regeneron
Pharmaceuticals, Inc. Tarrytown, NY
Self-Assembling Protein
Microarrays
Joshua LaBaer, M.D., PhD. Director, Harvard Institute of
Proteomics, Harvard Medical School, Cambridge, MA
Expression Profiling
in Support of Compound Selection
Petra Ross-Macdonald, PhD. Senior Research Investigator,
Bristol Myers-Squibb, Princeton, NJ
Semiconductor based
in situ synthesis of oligonucleotide microarrays
Andy McShea, PhD. Director, Applied Science, CombiMatrix
Inc. Mukileto, WA
Integrative Approaches
to Cancer: Biology, Biomarkers, and Bioinformatics
Arul M. Chinnaiyan, MD., PhD. Assistant Professor of Pathology
and Urology, University of Michigan Medical School, Ann
Arbor, MI
Transplantation
Biomarker Discovery and Validation
Yihong Yao, PhD. Abbott Bioresearch Center, Worcester, MA
Molecular characterization
of aging in human prefrontal cortex
Loubna Erraji-Benchekroun, PhD. Research Fellow, New York
State Psychiatric Institute, Columbia University, New York,
NY
Microarray
Analysis of HCV-Related Liver Diseases and HCV Model Systems
Jose Walewski, PhD. Assistant Professor of Medicine, The
Mount Sinai Hospital and Mount Sinai School of Medicine,
New York, NY
Exploring the use of Gene Expression-based in vivo Pharmacodynamic
Assays
Michael Mallamaci, Ph.D. Principal Scientist, AstraZeneca
Pharmaceuticals, Wilmington, DE
Gene expression profiling
for biomarker discovery
Kazuhiko Uchida, MD, PhD. Associate Professor, University
of Tsukuba & AIST, JAPAN
Photocleavable Fluorescent
Nucleotides for DNA Sequencing on a Chip Constructed by
Click Chemistry
Jingyue Ju, PhD. Associate Professor & Head of Columbia
Genome Center
Columbia University College of Physicians & Surgeons,
New York, NY
Slide surface chemistry
holds the key to a reliable and reproducible microarray
analysis
Muhammad A. Lodhi, PhD. Director, Diagnostics & Drug
Discovery, SurModics, Inc. Eden Prairie, MN
Microarrays and Diagnostics
in the Academic Environment: The Future of Technology, Bioinformatics
and Medicine
Andrew Brooks, PhD. Assistant Professor and Director of
Functional Genomics Center, University of Rochester Medical
School, Rochester, NY
A Next Generation Slide
Processing Platform for IHC, ISH, and Microarray Applications
Anis H. Khimani, Ph.D. Director, Marketing, Ventana Medical
Systems, Inc. Tucson, AZ
The LDL Receptor-Related
Protein 5 (LRP-5) Gene: Genomic Approaches for the Development
of New Targets for Osteoporosis
Eugene L. Brown, PhD. Senior Director, Expression Profiling
Sciences, Wyeth Research, Cambridge, MA
Multiplex Protein Quantification
using SearchLight? Proteome Arrays
Scott Van Arsdell, PhD. Associate Director of Research,
Pierce Biotechnology, Inc. Woburn, MA
High Throughput
MicroArrays with Nanopin M ceramic capillary pins and Ez-Rays
96 well microplates
Ezra S. Abrams, PhD. Director, Matrix Technologies Corp.
Hudson, NH
Diagnostic Applications of
Array Comparative Genomic Hybridization
Edward Chait, PhD. CEO, Spectral Genomics, Inc. Houston,
TX
Reverse Microarray of Depleted
Human Plasma Significantly Enhances Low Abundant Protein
Detection and Allows Disease Specific Protein Measurement
Sunny Tam, Ph.D. Manager, Charles River
Proteomic Services, Worcester, MA
TBA
Dennis McCormac, Ph.D. Director of Product Marketing, Iobion
Informatics, LLC, Toronto, Canada
Abstracts
Steps Toward
a Molecular Biology of Memory Storage
Eric Kandel, MD. Nobel Laureate 2000 (Physiology
or Medicine), University Professor, Senior Investigator
of Howard Hughes Medical Institute, Founding Director of
Center for Neurobiology & Behavior, Columbia University
College of Physicians and Surgeons, New York, NY
I would like
to consider two aspects of the molecular biology of memory
storage. First I will try to give you an overview of a conserved
core signaling mechanism that is used in a variety of different
contexts to convert short-term memory to long-term memory.
Second, I would like to focus on a potential mechanism that
can contribute to the persistence of memory storage over
a period of days, weeks or longer.
Expression Profiling in Support of Compound Selection
Petra Ross-Macdonald, PhD. Senior Research
Investigator, Bristol Myers-Squibb, Princeton, NJ
Pharmaceutical
compounds are subjected to an increasingly stringent traige
process, and yet still may have hidden liabilities of selectivity
that can be lead to expensive failures later in development.
We are analyzing the gene expression profiles of treated
cells to uncover such differences, providing an additional
and novel means of characterizing and prioritizing compounds.
We will discuss examples of this approach in several drug
discovery programs.
Noninvasive diagnosis of liver cirrhosis using DNA-sequencer-based
total serum protein glycomics
Roland Contreras, PhD. Professor of Molecular
Biology, Department of Molecular Biomedical Research, Ghent
University and Flanders Interuniversity Institute for
Biotechnology, Technologiepark 927, B-9052 Zwijnaarde, Belgium
Nico Callewaert1°,
Hans Van Vlierberghe2, Annelies Van Hecke1, Wouter Laroy1,
Joris Delanghe3 and Roland Contreras1
1 Department
of Molecular Biomedical Research, Ghent University and Flanders
Interuniversity Institute for Biotechnology, Technologiepark
927, B-9052 Zwijnaarde, Belgium
2 Department of Gastroenterology and Hepatology, Ghent University
Hospital, De Pintelaan 185, B-9000 Ghent, Belgium
3 Department of Clinical chemistry, Microbiology and Immunology,
Ghent University Hospital, De Pintelaan 185, B-9000 Ghent,
Belgium
° Current address: Swiss Federal Institute of Technology
(ETH), Schmelzbergstrasse 7, CH-8092 Zürich, Switzerland.
We developed
a 'clinical glycomics' method that uses a PCR thermocycler
and a DNA sequencer/fragment analyzer to rapidly generate
high-resolution profiles of the N-glycan post-translational
modifications present on the proteins in patient's serum
(see the Figure of this abstract). We have found that the
serum N-glycome yields a biomarker that diagnoses mild liver
cirrhosis with 90% efficiency (and advanced liver cirrhosis
with 100% efficiency). Highly specific serum biomarkers
such as the one described here are very valuable, as they
can help to obviate the biopsy need in a lot of cirrhosis
patients. Moreover, this biomarker could eventually be used
in routine follow-up of chronic liver disease patients,
to yield an early warning signal that cirrhosis has developed
and that complications (amongst others: hepatocellular carcinoma)
might arise. Our biomarker can easily be implemented in
the majority of the existing molecular diagnostics laboratories
at low cost.
Legionella
pneumophila: From genome to transcriptome
James J. Russo, Ph.D. Associate Head of
Sequencing and Chemical Biology
Columbia Genome Center, New York, NY
We recently
sequenced the genome of Legionella pneumophila, the causative
agent of Legionnaires’ disease. The 3.4 Mb genome
was mined for potential virulence genes, critical transporters,
unexpected metabolic pathways, and unstable elements. We
also identified sets of genes common to intracellular pathogens
and Legionella-specific expansions of critical genes occurring
singly in other bacteria. We produced a microarray based
on all the predicted genes that has been used for expression
studies on bacterial growth in wt and rpoS null strains;
BAC hybridization studies to confirm the genome sequence
assembly; and genome-to-genome DNA hybridization studies
to understand evolutionary relationships and lifestyles.
A Next Generation
Slide Processing Platform for IHC, ISH, and Microarray Applications
Anis H. Khimani, Ph.D. Director, Marketing,
MDS, Ventana Medical Systems, Inc. Tucson, AZ
.
Automated slide processing provides standardization and
reliability in applications such as immunohistochemistry
(IHC), in situ hybridizations (ISH), and microarray hybridizations,
including tissue microarrays. Ventana’s Discovery®
system has offered complete walk-away automation for assay
development in target identification and validation, and
in preclinical toxicology and biomarker development and
validation. The new Discovery® XT system enhances the
assay development and validation process with increased
capacity and greater consistency. Data from these applications
on numerous model systems will be presented.
Self-Assembling
Protein Microarrays
Joshua LaBaer, M.D., Ph.D. Director, Institute
of Proteomics, Harvard Medical School, Cambridge, MA
Protein microarrays
provide a powerful tool for the study of protein function.
However, they are not widely used in part because of the
challenges in producing proteins to spot on the arrays.
We generated protein microarrays by printing cDNAs onto
glass slides and then translating target proteins with mammalian
reticulocyte lysate. Epitope tags fused to the proteins
allow them to be immobilized in situ. This obviates the
need to purify proteins, avoids protein stability problems
during storage and captures sufficient protein for functional
studies. We used the technology to map pairwise interactions
among 29 human DNA replication initiation proteins, to recapitulate
the regulation of Cdt1 binding to select replication proteins,
and to map its geminin binding domain.
Molecular characterization
of aging in human prefrontal cortex
L. Erraji-Benchekroun, PhD. Department
of Psychiatry, Columbia University and Department of Neuroscience,
New York Sate Psychiatric Institute, New York, NY
L. Erraji-Benchekroun1,2,
H. Galfalvy1, V. Arango1,2, M.D. Underwood1,2, P. Smyrniotopoulos2,
P. Pavlidis3, J.J. Mann1,2, and E. Sibille1,2.
1. Dept. of Psychiatry, Columbia University, New York, NY,
USA, 2. Dept. of Neuroscience, NYSPI, New York, NY, USA,
3. Genome Center, Columbia University, New York, NY, USA
Aging leads
to morphological and functional changes in the brain, and
is associated with increased risk for numerous psychiatric
and neurological disorders. To identify normal age-related
transcriptional changes that occur in the human brain, we
used profiled gene expressions in two prefrontal cortical
areas that are involved in higher cognitive processes, Brodmann
areas 9 and 47. We identified a “molecular signature”
of aging, consisting of changes in expression levels of
at least 540 genes that were progressive throughout the
adult life. By combining estimates of cellular origins of
expression with large-scale functional analysis we found
that age-upregulated transcripts were mostly of glial origin
and related to inflammation, cellular defenses, structural
filaments, chromatin structure and signal transduction.
Genes downregulated with age revealed selective changes
in neuronal systems, including transcripts whose products
were associated with voltage-gated channel activity, calcium
regulation, G-protein-coupled receptor signaling and neuropeptide
activity. Our results provide robust molecular markers of
normal brain aging.
Supported by:
MH62185, MH40210, 5 T32 MH20004/05 & American Foundation
for Suicide Prevention
Application of Gene Expression Profiling to drug discovery
in Regeneron Pharmaceuticals
Yi Wei, Ph.D. Regeneron Pharmaceuticals,
Inc. Tarrytown, NY
Regeneron is
a biophamaceutical company that discovers and develops protein
therapeutics for the treatment of various diseases. We have
established a microarray facility to support different research
initiatives in Regeneron, using Agilent oligonucleotide
microarrays. We are going to present several examples of
the contributions of gene expression profiling to drug discovery
in Regeneron. First, gene expression profiling is used to
phenotype knock-out mice coming out of our Velocigene program,
a high throughput system of producing knock-out mice. Second,
gene expression profiling is used to elucidate the molecular
mechanisms underlying angiopoietin-1, an essential regulator
of vascular development. And last, gene expression profiling
is used to look for new targets in angiogenesis therapy
for cancer.
Multiplex Protein
Quantification using SearchLight? Proteome Arrays
Scott Van Arsdell, PhD. Associate Director
of Research, Pierce Biotechnology, Inc. Woburn, MA
SearchLight?
Proteome Arrays are multiplexed sandwich ELISAs for the
quantitative measurement of 2 to 25 proteins per well offering
excellent sensitivity, small sample volume, compatibility
with plate-based equipment, and a broad menu of proteins.
This presentation will review the SearchLight technology,
the array configurations currently available, and the instrumentation
and array software utilized to generate results. In-house
data from various stimulation and time course studies will
be presented. General performance data exhibiting the specificity,
accuracy, and reproducibility of the arrays and the various
ways that the SearchLight? technology can be accessed (analysis
system, custom array development, and sample testing services)
will also be discussed.
High Throughput
MicroArrays with Nanopin M ceramic capillary pins and Ez-Rays
96 well microplates
Ezra S. Abrams, PhD. Director, Matrix Technologies
Corp. 22 Friars Drive, Hudson, NH
Ezra S Abrams;
C. Boles; J. Melo; S. Mielewczyk; B. Patterson; B. Stone
Matrix Technologies, 22 Friars Drive, Hudson NH
The Nanopin M is a ceramic capillary pin designed for contact
printing of microarrays. With a closed capillary design,
several hundred spots can be printed from each source visit,
and speed is further increased because little or no pre-blotting
is needed. Nanopin M pins have good pin to pin reproducibility,
due to the precise manufacturing process, and new pins can
be added to a set of “old” pins at any time,
as the hard ceramic material does not wear or deform. We
have used Nanopin M ceramic pins to print DNA microarrays
on both slides (ez-rays amino-silane or ez-rays universal)
and on ez-rays plates, which are 96 well glass bottom microplates
with ez-rays universal coating. The combination of ceramic
pins and plates allows the researcher to print, in a single
run, >1,000 arrays, each with up to several hundred probes.
Gene expression
profiling for biomarker discovery
Kazuhiko Uchida, MD., PhD. Associate Professor,
University of Tsukuba and Clinical Bioinfomatics Research
Initiative, AIST, Tsukuba, Ibaraki, JAPAN
Cancer diagnostics
and therapeutics are often based on clinically relevant
markers that are expressed specifically in a malignant tissue
at levels higher than in normal tissue. Gene expression
profiles for papillary thyroid carcinoma, normal thyroid
tissue, and healthy peripheral blood cells using a human
4K-gene in-house cDNA microarray and GeneChip U133 45K array
and immunohistochemistry of the up-regulated gene products
identified PDGF as a protein that are specifically expressed
at high levels in thyroid neoplasms. Thus, expression profile
analysis using a microarray followed by an immunohistochemical
study can be used to facilitate the development of molecular
biomarkers for cancer.
Photocleavable
Fluorescent Nucleotides for DNA Sequencing on a Chip Constructed
by Click Chemistry
Jingyue Ju, PhD. Associate Professor &
Head of Columbia Genome Center and Department of Chemical
Engineering, Columbia University College of Physicians &
Surgeons, New York
DNA sequencing
by synthesis on a solid surface during polymerase reaction
offers a new paradigm to decipher DNA sequences. We report
the design of such a novel DNA sequencing system using chemical
and molecular engineering approaches. The design rationale
of the system is to use 4 distinct fluorescent emissions
to code for the identity of the 4 nucleotides (A, C, G,
T) during DNA polymerase reaction. We have designed and
synthesized 4 photocleavable fluorescent nucleotides for
such a system and established a covalent and chemoselective
1,3-dipolar azide-alkyne cycloaddition coupling chemistry
for immobilizing DNA on a chip. DNA sequencing results from
such a system will be presented.
Exploring the
use of Gene Expression-based in vivo Pharmacodynamic Assays
Michael Mallamaci, PhD. Group Leader, Principal
Scientist, AstraZeneca Pharmaceuticals, Wilmington, DE
A major component
of the drug discovery process is the use of animal models
to demonstrate in vivo efficacy and to optimize basic in
vivo drug properties. Unfortunately, in many cases the number
of compounds that can be tested is limited by the time and
expense associated with the assays; this is especially true
of CNS models with a behavioral readout. What is needed
is a primary in vivo assay that employs a simple but reliable
marker that measures a drug effect in the CNS. This assay
can be used to establish many of the pharmacodynamic properties
of the compound prior to in vivo functional testing. The
use of both global and specific quantitative gene expression
profiling platforms for the development and implementation
of in vivo pharmacodynamic assays will be discussed.
Reverse Microarray
of Depleted Human Plasma Significantly Enhances Low Abundant
Protein Detection and Allows Disease Specific Protein Measurement
Sunny Tam, Ph.D. Manager, Charles River
Proteomic Services, Worcester, MA
We have developed
a high-throughput depletion protocol using chicken IgY antibodies
(GenWay Biotech) that are capable of removing abundant proteins
such as albumin or IgG from plasma and serum across multiple
mammalian species. By using the IgY antibodies in an automated
liquid chromatography system, the depleted sera and the
abundant protein associated complexes can be microarrayed
and archived using the Zeptosens reverse array platform.
The depletion methodology also further increases the detection
range of low abundant proteins, such as antithrombin III
and interleukins. Furthermore, by lowering the protein complexity
of the samples through depletion, a more accurate disease
specific protein measurement can be obtained.
Diagnostic
Applications of Array Comparative Genomic Hybridization
Edward Chait, PhD. CEO, Spectral Genomics,
Inc. Houston, TX
Johnson, Robert
C., Xin Yan Lu, Scott Hutto, Jae-weon Kim and Edward Chait.
Spectral Genomics, Inc., Houston, TX
Array Comparative
Genomic Hybridization using Bacterial Artificial Chromosomes
(BACs) printed on glass slides provides a means of evaluating
chromosomal structure changes across the entire genome in
one assay. Spectral Genomics, Inc. manufactures SpectralChip™
that contains 2600 BACs printed in duplicate for research
purposes and its Constitutional Chip™ containing 464
BACs printed in triplicate for research in the area of constitutional
syndromes. These microarrays have been used to detect copy
number changes in tumor samples at a resolution of approximately
1Mb and thereby provide a much more sensitive method to
identify chromosomal changes than conventional cytogenetics
approaches. The microarrays also have utility in detecting
deletions and amplifications diagnostic for a wide range
of syndromes. The Constitutional chip™ is specifically
designed for identification of a number of microdeletion
syndromes traditionally detected by FISH assays. In essence,
the microarrays perform hundreds or thousands of FISH assays
at one time and thereby act as a high capacity screening
tool for detection of disease associated with DNA structural
changes.
Zooming In:
Moving from Genome-Wide Expression Profiling to High-Throughput
Fingerprint Screening
Jay P. Tiesman, PhD. Procter & Gamble,
Miami Valley Labs, PO Box 538707, Cincinnati, OH 45252-8707
Jay P. Tiesman,
Suzanne M. Torontali, Kenton D. Juhlin, M. Lynn Jump1, Brian
D. Richardson2, Kerry G. Oliver3, George P. Daston, Jorge
M. Naciff
Procter & Gamble, Miami Valley Labs, Cincinnati, OH
1Procter & Gamble, Health Care Research Center, Mason,
OH
2Cincinnati Children's Hospital Medical Center, Cincinnati,
OH
3Radix BioSolutions, Georgetown, TX
A primary goal
of genome-wide expression profiling is to identify subsets
of gene transcripts that can be associated with specific
biological conditions. Once these gene expression “fingerprints”
have been elucidated, they can be used in screening assays
to identify molecules that induce similar gene expression
changes. To increase the throughput of these screening assays,
we have optimized the development of a bead-based, flow-cytometric
platform that allows the high-throughput screening of up
to 100 transcripts per sample in a 96-well plate format.
We have achieved detection levels down to 1 attomole per
analyte, which allows the detection of rare messages in
complex cRNA samples. This presentation will describe the
development of this assay as well as outstanding technical
issues currently being addressed. It is anticipated that
this technology will be a useful secondary screening platform
for high-throughput gene expression fingerprinting.
Slide Surface
Chemistry Holds the Key to Reliable and Reproducible Microarray
Analyses
Muhammad A. Lodhi, PhD. Director of Diagnostics
and Drug Discovery, SurModics, Inc. Eden Prairie, MN
Muhammad A.
Lodhi and Gary W. Opperman, Diagnostics and Drug Discovery,
SurModics, Inc. Eden Prairie, MN
Microarray
analysis is characterized by simultaneous detection of multiple
hybridizations and/or molecular interactions of surface-bound
probes to free-floating targets in solution. Due to the
complex nature of microarrays, each component, from substrate
to surface chemistry and from probe content to the detection
system, plays a critical role in the final outcome of the
analyses. Recently, several individual laboratories and
consortia have run comparisons on commercial microarrays
and found variable, and in some cases, contradictory results.
In this presentation, the contribution of surface chemistry
to the overall variability of the results will be discussed.
Transplantation
Biomarker Discovery and Validation
Yihong Yao, PhD. Senior Scientist, Abbott
Bioresearch Center, Worcester, MA
Wider Implementation
of biomarker strategies promises to help meet unmet medical
needs as well as enable more economical clinical development.
Biomarkers fall into many classes that can be used to meet
different needs. Surrogate end points are biomarkers predicting
efficacy, with proper validation these can be used to support
FDA registrations. Phenotypic and genotypic biomarkers can
be used to classify patient populations and indicate appropriate
treatments or susceptible populations. Pharmacodynamic biomarkers
(PDBMs) can be used to measure acute target inhibition without
measuring efficacy. These biomarkers are potentially useful
in determining dose during clinical trials and after approval.
We have taken a microarray approach to discovering PDBM’s
useful for monitoring compounds used to prevent organ graft
rejection. Using a panel of normal subjects and T cell activation
models we have identified a set of markers that respond
to proprietary and currently marketed compounds such as
FK506. We will present details of the processes leading
to the discovery and validation of these markers.
Please contact
if you are interested in speaking in the scientific or Technology
workshops of this meeting.
• Six speakers will be chosen from Academia includes
Rockefeller, Cornell, Columbia, NYU and Sloan Kettering.
• Six speakers will be chosen from the Biotech industry.
• Ten speakers will be chosen from the Pharmaceutical
industry.
Panel Discussion on July 27th with experts from:
- Venture Capital Firm, New York, NY
- Technology Licensing Manager from NYC University, New
York, NY
- A Patent Attorney from Intellectual Property Law Firm,
New York, NY
- Professional Science/Business Journalists
- Professional Business Journalist (either from NY Times
or Wall Street Journal or Business Week)
- Selected Academic Speaker from the meeting.
- Selected Industry Speaker/Executive from the meeting.
Exhibitors
are welcome to reserve their booth space.
GeneExpression
Systems, Inc.
P.O. Box 540170
Waltham, MA 02454 USA
Tel: (781) 891-8181
Fax: (781) 891-8234
E-mail: Genexpsys@expressgenes.com
www.expressgenes.com
BioArrays-2003-New York Meeting Testimonials
“If I compare the presentations
at BioArray 2003 with any innovative technology meetings,
they would rank among the top work in the field.”
- Prof. Francis Barany, Cornell and Rockefeller University
“It was very well
organized and a productive meeting for me.” –
Dr. Eric Eastman, CSO, MetriGenix
“It is very nicely
integrated scientific meeting to demonstrate the new technology
with very limited industrial marketing compared to any other
meetings.” - Dr. Charles Tackney, Director, Ortho-Clinical
Diagnostics and Johnson & Johnson
“This is an excellent
and relevant meeting for me to learn the basics and apply
in the clinic.” - Prof. Joe Lunec, Univ. of Leicester,
UK
“Truly a fascinating
theme to gather experts in the field.” - Prof. Victor
Barsky, Russian Academy of Sciences, Moscow, Russia
“Very well balanced meeting chosen to have excellent
speakers in the field, and gave me full understanding of
array technology and how it could be well applied to understand
the diseases and diagnostics.” - Dr. Elisa Wurmbach,
Mount Sinai School of Medicine, New York
“Excellent mix
of technology and scientific talks; an outstanding agenda.”
- Fiona Stewart, Business Development, New England Biolabs
To
view the details of 2003 meeting Sponsors, Posters, Awards,
and Surveys please visit our main page and click After BioArrays-2003
Meeting information.