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GeneExpression Systems of USA and University of Cambridge of UK
Appasani Research Conferences (ARCEI.ORG)

Jointly Presents

MicroRNAs & END Europe - 2015 Symposia

10th International
MicroRNAs & NonCoding RNAs Europe 2015 Meeting
MicroRNAs/NcRNAs: Biology to Development and Disease

Third International
European Neurodegenerative Diseases/Optogenetics Europe 2015 Meeting
Neurobiology to Brain Mapping, Optogenetics & Disease Therapeutics


November 2 - 3, 2015

Venue: Peterhouse, University of Cambridge, Cambridge, UK

A Unique Theme Conference & Exhibition in the MicroRNomics & Optogenetics

Meeting Place:

The Venue Peterhouse (middle) is the oldest College of the University of Cambridge, founded in 1284 and an institution dedicated to education and research. Throughout its history, Petreans have been at the heart of the political, social and religious controversies that have shaped today’s society. Some of the influential Petreans include: Henry Cavendish, Lord Kelvin, Sir Frank Whittle and Christopher Cockerill, and Nobel Laureates – Sir John Kendrew, Sir Aaron Klug, Archer Martin and Max Perutz , who gave a twentieth century lead in the field of Molecular Biology. Since many centuries it remained as a hub for innovation and successive generations of the brightest young people around the world.

Why do you wait to join for an intellectual gathering in the ‘microRNomics’ & 'END-Optogenetics' arenas at the prestigious college Peterhouse in the Premier University campus!

Expected Maximum Capacity:
Target Audience 100
Total Speaker Presentations: 30
Total Poster Presentations: 10
Total Exhibit Booths: 5


The purpose and scope of this two-day intensive unique and intellectual European Symposia - 2015 (on November 2 – 3, 2015) is to provide a forum for the discussion of the current state of the art of rapidly evolving MicroRNAs/ Noncoding RNAs, Single Molecule Biology, Genome Engineering/Editing and Neurodegenerative Diseases/Optogenetics highly interdisciplinary emerging fields in biomedicine and biotechnology fields. This will consists of three parallel theme meetings:

1. MicroRNAs & Noncoding RNAs Europe - 2015: This is our 10th international theme conference continuously held in this college in the first week of November in Cambridge, England. Professors Julie Ahringer and Eric Miska of the University of Cambridge inaugurated our first meeting in November 2006. Since then, Nobel Laureates Drs. Tim Hunt, John Walker; and pioneers in MicroRNAs fields including: Drs. David Baulcombe (UK), Carlo Croce (USA), Gunter Meister (Germany), Mike Gait (UK), Rene Ketting (Germany) and many more have given keynote speeches. MicroRNAs/Noncoding RNAs are the “biology’s Big Bang” and we are igniting the spirit of both  Micro/LNcRNomics in order to understand the biology of these molecules and their pivotal role(s) in diseases in order to develop innovative products based on this technology platform.

. European Neurodegenerative Diseases/Optogenetics Europe - 2015: This is our 3rd international theme conference to be held on November 2-3, 2015 at the Peterhouse College, Cambridge, England. The first meeting was held in September 20-21,2010 in Oriel College of the University of Oxford, UK, the Second one held in October 10-11, 2011 in CNR-Institute, Tor Vergata-Rome, Italy. Pioneers in Neuroscience and Neurology fields including: Drs. Anthony Monaco (UK), Joan Fallon (USA), John Collinge (UK), Antonio Cattaneo (Italy) and many more have given keynote speeches. In recent years there is a great trend emerging in understanding the biology of neuron to synapses and their defects in memory, learning and cognition. Specially, to decipher the ‘Brain Code and Mapping’ novel technique such as Optogenetics has been adopted to study connectomics and to develop brain-interface devices to treat several neurodegenerative/neuro psychotic diseases. Therefore, this meeting will focus on the disease biology of neuro/synaptic disorders and how one can fix these problems with optogenetics and how to develop novel drug targets using this technology platform.

In this international meeting, prominent researchers (Developmental biologists, cell biologists, geneticists, molecular biologists, computational biologists, neurobiologists, clinicians, chemists, bioengineers, synthetic biologists and physicists)  from both academia and industry will gather and discuss the applications in form of keynote lectures, invited talks, short oral, and poster presentations.
These meetings are open for graduate students, postdoctoral fellows and professors from academia and research scientists and executives from bio-pharma industry to gain insights in the emerging frontiers in biotechnology.

Venue: The Venue Peterhouse is the oldest College of the University of Cambridge, located close to the banks of Cam River. This college has produced science giants such as: Henry Cavendish, Lord Kelvin, Sir Frank Whittle and Christopher Cockerill, and Nobel Laureates – Sir John Kendrew, Sir Aaron Klug, Archer Martin and Max Perutz. Participate in this meeting and become proud attending member of this prestigious college in the world.

Note: All the members (except keynote speakers and others who arranged with organizer) who participate in this symposium have to register for the meeting by paying the appropriate registration fee. All the registered participants has the leverage to attend any parallel session they are interested

Click Here for Agenda

Monday, November 2, 2015
8:00A.M: Registration Open 
8.45 AM – 6.30 PM Scientific Sessions 

Tuesday, November 3, 2015
8:00A.M: Registration Open 
9.00 AM – 6.00 PM Scientific Sessions

Scientific Organizer:

Krishnarao Appasani, PhD., MBA
Founder & CEO
GeneExpression Systems, Inc
Waltham, MA USA

Key Sessions:

MicroRNAs/NonCoding RNAs & Editing

END & Optogenetics

  • MicroRNAs &NcRNAs Discovery and Biogenesis
  • MicroRNAs &NcRNAs in Development
  • Bioinformatics of MicroRNAs & Long NcRNAs
  • MicroRNAs &NcRNAs in Stem Cell Biology
  • MicroRNAs &NcRNAs-mediated Epigenetic Regulation
  • MicroRNAs &NcRNAs in Disease Biology
  • MicroRNAs &NcRNAs in Metabolic & Cardiovascular systems
  • MicroRNAs &NcRNAs in Cancer Biology
  • MicroRNAs in Virology & Diagnostics
  • Therapeutic Applications of MicroRNAs &NcRNAs
  • Biology, Design and Delivery of Nucleases (ZFNs & TALENs)
  • RNA-guided genome engineering/editing with Cas9/CRISPRs
  • High throughput genome editing & Therapeutic applications
  • Generation of ZFN/TALEN-mediated knockout animals and cell lines
  • Targeting optogenetic tools in vivo and in vitr
  • Neural plasticity, Connectomics, Cognition & Behavior
  • Optogenetics applications in Stem Cell/Cardiac & Disease Biology
  • Biochemistry of light-mediated Opsin proteins & Gated channels
  • Light sources, delivery& Spatiotemporal Targeting
  • Mapping cellular memory engrams & Imaging of neuronal circuits and networks
  • Crystallography, Microscopy & Spectroscopy of optogenetic molecules
  • Photochemical/optoelectric/optofluidic activation 
  • Probing Neurodegenerative and Psychiatric disorders
  • Therapeutic Development for Neurodegenerative Diseases

Keynote Speakers:

Eric A. Miska, PhD.
Herchel Smith Professor of Molecular Genetics &
Senior Group Leader at the Gurdon Institute
University of Cambridge
Cambridge, United Kingdom
Title: Transgenerational epigenetic inheritance and RNAe 
Joan Fallon, PhD.                                        
Chief Executive Officer
Curemark, Inc.
Rye, NY, USA
Title: Role of amino acid and brain transcription factors in neurodegenerative diseases
Gero Miesenböck, MD. FRS
Waynflete Professor of Physiology   
Director, Centre for Neural Circuits and Behavior
University of Oxford
Oxford, United Kingdom
Title: Light Sleep

Other Speakers:

Micro/NonCoding RNAs & Editing END & Optogenetics
Anna Git, PhD.
Researcher at Cancer Research UK
Cambridge Research Institute
University of Cambridge
Cambridge, United Kingdom
Title: miRNAs in breast cancer – the landscape, the function and the woes of validation
Albrecht Stroh, PhD.
Professor of Anatomy and Neurobiology
Johannes Gutenberg-University Mainz
Mainz, Germany
Title: From correlations to causality: Combining high-field fMRI, optogenetics and optical calcium recordings in rodents
Paul S. Foster, PhD, DSc.
Laureate Professor
Hunter Medical Research Institute &
University of Newcastle, Callaghan, Australia
Title: MicroRNAs in lung diseases
Linda Greensmith, PhD.
Professor Neuroscience
UCL Institute of Neurology
University College London
London, UK
Title: Using Optogenetics and stem cell-derived neural grafts to restore motor function
Hermona Soreq, Ph.D.
Professor of Molecular Neuroscience
The Edmond and Lily Safra Center for Brain Sciences
The Hebrew University of Jerusalem
Jerusalem 91904, Israel
From Mice to men: MicroRNA regulators of stress-induced cholinergic signaling
Christof Taxis, PhD.
Junior Group Leader
Philipps-Universität Marburg
Marburg, Germany
Title: Development and application of an optogenetic tool for synthetic regulation of protein stability
Yoko Matsuno, MD. PhD.
Niigata University, Graduate School of Medicine
Niigata-shi, Niigata, Japan
Title: Xist/XIST RNA and possible triplex formation for localization to chromatin with redundancy
Julia Krupic, PhD.                            
Sir Henry Wellcome Postdoctoral Fellow
Cell & Developmental Biology
University College London
London, UK
Title: Mechanism of grid cell pattern formation and large place cell network sin para-hippocampal region
  Aida Margarita Zamora-Contreras                        
Department of Genetics & Molecular Biology
Cinvestav, Mexico
Title: Evaluation of let-7 microRNA family and their targets expression in Cervical Carcinoma Cell Lines
Michel Goedert, MD., FRS., FMedSci.
Professor of Neurobiology
MRC-Lab of Molecular Biology
Cambridge, UK
Title:Tauopathies and alpha-synucleinopathies and at identifying disease modifiers
Fiona Furlong, PhD.
Lecturer of Pharmacology
Queens University Belfast,
Belfast, UK
Title: A miR-433 mediated mechanism of chemoresistance
Minako Hoshi, PhD.
Associate Professor Anatomy &Dev. Biology
Kyoto UniversitySchool of Medicine
Kyoto, Japan
Title: Na+, K+-ATPase alpha 3 is a new death target of Alzheimer amyloid-beta assembly
Marc Winnefeld, PhD.
Head of Research Special & Aged Skin Lab
Beiersdorf AG
Hamburg, Germany
Title: Identification of microRNAs involved in skin aging
Eilís Dowd, PhD.
Senior Lecturer in Pharmacology
Galway Neuroscience Institute
National University of Ireland
Galway, Ireland
Title: Gene-environment interactions as an approach to modelling Parkinson’s disease
Isabelle Mansuy, PhD.
Professor at Brain Research Inst.
University/ETH Zürich
Zürich, Switzerland
Title:NoncodingRNAs in trans-generational inheritance
Karl Emanuel Busch, PhD.
Chancellor's Fellow
Center for Integrative Physiology
University of Edinburgh
Edinburgh, Scotland-UK
Title: The long and the short of sensory processing in C. elegans
Antonello Mallamaci, PhD.
Associate Professor in Molecular Biology &
Head of the Lab. of Cerebral Cortex Development
SISSA, Trieste, Italy Title: Upregulating endogenous genes by an RNA-programmable artificial transactivator"
Dr. Massimo De Vittorio                             
Director of the Center for Biomolecular Nanotechnologies
IstitutoItaliano di Tecnologia&Universitàdel Salento
Lecce, Italy
Nanomachined tapered optical fibers for optogenetics
    Rosemary Fricker, PhD.
Reader in Biomedical Sciences
Keele University
Hatshill, Stoke-on Trent, UK
Title:Vitamins B3 and D3 influence the development and survival of midbrain dopamine neurons. 
Rintaro Hiraide
PhD student in Pathology
Univ. of Cambridge-Addenbrooke's Hospital
Cambridge, UK
Title: Interferon-induced long noncoding RNA in swine
  Dr. Claire Kelly
Lecturer in Biomedical Science
Cardiff Metropolitan University
Cardiff, Wales, UK
Title: Making medium spiny neurons for neural transplantation
Fergal J. O'Brien, PhD.
Professor & Deputy Director of Research
Royal College of Surgeons in Ireland
Dublin, Ireland
Title: Collagen-based scaffolds for microRNA delivery to enhance tissue regeneration
Deepak P. Srivastava PhD.
Lecturer in Neurobiology
King's College London
London, United Kingdom
Title: Impact of susceptibility genes on the synaptic connectivity in psychiatric disorders studied with use of human neural stem cells and super-resolution imaging
Marie-Laure Baudet, PhD.
Principal Investigator
Ctr. for Integrative Biology-Univ. of Trento, Trento, Italy
Title: microRNAs: subcellular action in neurons during brain wiring
Giuseppe Sciamanna, PhD.
Associate Researcher
Univ. of Rome “Tor Vergata
Tor Vergata, Rome, Italy
Title: Role of Rhes in striatal physiology: a potential new target in L-Dopa-induced dyskinesia Pathophysiology of Parkinson’s disease and dyskinesia
Lyudmila Gulyaeva, PhD. DB.
Professor at the Institute of Molecular Biology & Biophysics
Russian Academy of Medical Sciences&
Novosibirsk State University
Novosibirsk, Russia
Title:Effect of long term exposure of DDT on microRNA expression in rat female organs
  Lad Yatish, PhD.
Oxford BioMedica (UK) Ltd.,
Oxford, OX4 4GA, UK
Title: Gene therapy for the treatment of Parkinson’s disease
Ping Gao, PhD.
Professor of Life Sciences 
Univ. of Science & Technology of China
Hefei, Anhui, P.R. China
Title: The roles of miRNAs in regulating Warburg Effect in cancer cells as well as in stem cells
Dr. Kerensa Broersen-Nutma
Assistant Professor of Nanobiophysics
MIRA Institute-University of Twente
Enschede, The Netherlands
Title: Role of amyloid proteins in Alzheimer’s disease
Pieter Mestdagh, PhD.
Researcher at Center for Medical Genetics
Ghent University Hospital
Ghent, Belgium
Title: Non-coding RNAs in cancer as novel biomarkers and therapeutic targets
Peter Nilsson, PhD.
Professor &Vice Dean School of Biotechnology
KTH – Royal Institute of Technology
Solna, Sweden 
Title: Human Protein Atlas enabled neuroproteomic profiling of body fluids
Bernard A.J. Roelen, PhD.
Associate Professor
Utrecht University
Utrecht, The Netherlands
Title: piRNAs in mammalian oocytes
Anna Häggmark, PhD.
Postdoctoral Scientist at SciLifeLab
KTH – Royal Institute of Technology
Solna, Sweden
Title: Proteomic plasma profiling within ALS
Andrew Bassett, PhD.
Head of Genome Engineering Oxford
Sir William Dunn School of Pathology
University of Oxford, Oxford, UK
Title: Investigation of miRNA function using genome engineering
Peter Vangheluwe, PhD.
Associate Professor of Cellular & Molecular Medicine
Catholic University of Leuven
Leuven, Belgium
Title:Unlocking ATP13A2/PARK9 activity protects against mitochondrial stress
Oluf Dimitri Røe, MD. & PhD.
Oncologist/Researcher in Cancer Clinic
SykehusetLevanger& NTNU
Trondheim, Norway
Title: Early diagnosis of lung cancer and mesothelioma by multi-omics, techniques and feasibility
Victoria Lunyak, PhD.
Founder, CEO and President
Aelan Cell Technologies, Inc.
San Francisco, CA, USA 
Title: TBA     
Kosuke Yusa, Ph.D.
Group leader in Stem Cell Genetics
Wellcome Trust Sanger Institute
Hinxton, Cambridge, United Kingdom
Title: Genome-wide functional screening using the CRISPR-Cas9 system
Samantha Barichievy, PhD.                        
Senior Research Scientist
Astra Zeneca R & D
Mölndal, Sweden
Title: Non-coding RNAs and HIV
Shawn Ahmed, PhD.
Professorof Genetics
University of North Carolina
Chapel Hill, NC, USA
Title: Adult Reproductive Diapause in response to piRNA dysfunction
Rachael Huntley, PhD.
Sr. Res. Associatein Cardiovascular Science
University College London
London, UK
Title:Functional annotation of cardiovascular-related miRNAs using the Gene Ontology
Dr. David Simpson                                      
Senior Lecturer in Experimental Medicine
Queen's Univ. Belfast & Royal Victoria Hospital
Belfast, UK
Title: Small RNA profiling in plasma
Zuzsanna Izsvak, PhD.
Group Leader
Max Delbruck Center for Molecular Medicine
Berlin, Germany
Title: Genome editing by transposable elements

* Presenting Speaker names, title and times are subject to change.
Host organization, organizer, or scientific committee does not take any kind of responsibility.

Exhibitors are welcome to reserve their booth space early!

Please contact if you are interested in speaking in the scientific or Technology workshops of this meeting.

GeneExpression Systems, Inc.
P.O. Box 540170
Waltham, MA 02454 USA
Tel: (781) 891-8181
Fax: (781)730-0700 or (781) 891-8234
E-mail: Genexpsys@expressgenes.com

Note: Speakers Names, Titles and venue subjected to change beyond our control for which the company is not responsible.

Oral Prentation Abstract Submission by September 24, 2015
Poster Abstract Submission by October 25, 2015

Email your abstract (100-200 words in word format) to: genexpsys@expressgenes.com

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