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GeneExpression Systems, Inc &
Appasani Research Conferences and Educational Institue (
Jontly Presents

10th International
RNAi, MicroRNAs & Single Cell Biology -2013 Meeting

May 1 - 2, 2013

Venue: Hilton Garden Inn, 420 Totten Pond Road, Waltham 02451, USA

This meeting will be held in Conjunction with Stem Cells and Optogenetics-2013-Meetings.


The Most Popular and The Best Global Event in the RNAi Field!

Expected Maximum Capacity:
Target Audience 100
Total Speaker Presentations: 30
Total Poster Presentations: 15
Total Exhibit Booths: 10

10th International Third International

RNAi, MicroRNAs & Oligos-Boston-2013 Meeting
RNA interference & MicroRNAs: Biochemistry to Drugs & Therapeutics

Single Cell Biology & Real-Time PCR-Boston-2013 Meeting
Single Molecule Detection to Amplification & Molecular Imaging
The Unique Theme to Combine Gene Silencing with Oligo Therapeutics!

The Unique Theme to Combine Biology & Chemistry with Microfluidics!

Key Sessions
Key Sessions
  • The Genetics of RNAi and microRNAs
  • RNAi, Oligos delivery in vivo, in vitro
  • microRNAs and their diverse roles in biology & disease
  • Computational and Disease Biology of miRNAs
  • Chemical synthesis of peptides and oligos
  • Large scale manufacturing and process development
  • Drug Target identification and Validation
  • High throughput genome-wide screenings
  • Development of Oligos and Peptide as Therapeuti
  • Clinical Application of Oligos and Peptides
  • Single Molecule Biology & RTPCR Assays
  • Single cell qPCR in Stem cells, tumor cells
  • Fluorescence Spectroscopy & Correlation Microscopy
  • Single Molecule Genomics
  • Atomic (Single Molecule) Force Microscopy
  • Bioscrening, Microfluidics, Fluorescence in Living cells
  • High throughput qPCR & Chip-integrated platforms
  • Fluorescent proteins and in vivo Analysis
  • Imaging gene expression in living cells at single molecule level


Wendnesday, May 1, 2013
8:00 A.M: Registration Open
8:45 AM – 6.30 PM Scientific Sessions

Thursday, May 2, 2013
8 A.M: Registration Open
9:00 – 6:15 PM: Scientific Sessions

Scientific Organizer:

Krishnarao Appasani, PhD., MBA
Founder & CEO
GeneExpression Systems, Inc
Waltham, MA USA

Scientific Committee:
Carl D. Novina MD, PhD.
Associate Professor of Microbiology & Immunobiology
Harvard Medical School &
Associate Member, Broad Institute of Harvard
Massachusetts Institute of Technology
Boston, Massachusetts, USA

Keynote Speakers:

Alexander Schier, PhD.
Professor of Molecular & Cellular Biology
Harvard University
Cambridge, MA, USA
Title: Identification of long non-coding RNAs

Rachel Meyers, PhD.
Vice President Research & RNAi Lead Development                      
Alnylam Pharmaceuticals, Inc.
Cambridge, MA, USA
Title: Moving siRNA-conjugates toward the clinic

Other Speakers:

Thomas Duchaine, PhD.
Associate Professor of Biochemistry
Goodman Cancer Center-McGill University
Montreal, Quebec, Canada
Title: A non-canonical site unveils multiple cooperative mechanisms in microRNA-mediated silencing

Ulrike Philippar, PhD.
Principal Scientist in Oncology
Merck Research Laboratories
Boston, MA, USA
Title:  Optimization of lipid nanoparticles and siRNA conjugates for enablement of siRNA therapeutics

Pål Sætrom, DPhil.
Professor of Bioinformatics
Norwegian University of Science & technology
Trondheim, Norway
Title: Finding SNPs that affect microRNA regulation
Daniel G. Anderson, PhD.
Associate Professor of Chemical Engineering
David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
Cambridge, MA, USA
Title: Combinatorial development of biomaterials and synthetic siRNA delivery systems
Thou Pederson, PhD.                                  
Vitold Arnett Professor of Biochemistry & Molecular Pharmacology
University of Massachusetts Medical School
Worcester MA, USA
Title:  MicroRNAs and messenger RNAs in the Nucleolus
Jiannis Ragoussis, PhD.                                         
Head of Genome Sciences
McGill University, Montréal, Canada
Title: microRNA-Associated Progression Pathways and Potential Therapeutic Targets Identified by Integrated mRNA and microRNA Expression Profiling in Breast Cancer
Alla Grishok, PhD.               
Assistant Professor of Molecular Biophysics
Columbia University-College of Physicians & Surgeons, New York, New York, USA
Title: Gene regulation by endogenous RNAi in C. elegans
Fabien Florent Pinaud, PhD.
Assistant Professor of Biological Sciences & Chemistry
University of Southern California
Los Angeles, CA, USA
Title: Targeting and tracking of individual proteins in live animals with nanometer accuracy
Shusheng Wang, PhD.
Assistant Professor
Tulane University
New Orleans, LA, USA
Title: Functional study of microRNA-23~27~24 in ocular angiogenesis
Amy E. Pasquinelli, Ph.D.
Associate Professor of Molecular Biology
University of California at San Diego
La Jolla, California, USA
Title: The primary target of let-7 microRNA
Amanda Birmingham
Bioinformatics Manager
Thermo FisherScientific
Lafayette, CO, USA
Title: Better than the real thing: In Silico screens for statistical selection
Carl D. Novina MD, PhD.
Associate Professor of Microbiology & Immunobiology
Harvard Medical School &
Boston, MA, USA
Lost in translation: the biology of mammalian microRNAs
Yuichi Taniguchi, PhD.
Unit Leader of Single Cell Gene Dynamics
RIKEN Quantitative Biology Center
Osaka, Japan
Title:Towards understanding heterogenous gene expressions at single cell levels

Jonathan Cohen, PhD.
Researcher in Porter Neuroscience Research Ctr.
NICHD-National Institutes of Health
Bethesda, MD, USA
Title: Bioinformatics, microRNAs, and synaptic plasticity

Masahiko Kuroda, MD, PhD.
Professor, Chair of Molecular Pathology &
Director of Bonac Corp.
Tokyo Medical University
Tokyo, Japan
Title: Significance and applications of novel class of RNA for cancer therapy

Patrick Y. Lu, PhD.
President & Chief Executive Officer
Sirnaomics, Inc.
Gaithersburg, MD, USA
Title: Development of three generations of nanoparticles for novel siRNA therapeutics

Brian L. Murphy, PhD. 
Research Fellow in Tumor Cell Biology
St. Jude Children's Research Hospital
Memphis, TN, USA
Title: Silencing of the miR-17~92 cluster by tiny LNAs suppresses Sonic Hedgehog medulloblastoma progression in vivo
Douglas Fambrough, PhD.
Chief Executive Officer
Dicerna Pharmaceuticals, Inc.
Watertown, MA, USA
Title: Delivery and efficacy of dicer substrate siRNAs (DsiRNAs) using EnCore lipid nanoparticles in multiple tumor models
Matthew Hsu, PhD.
Director of R&D - Bioscience Division
Merck Millipore
Temecula,California, USA
Title: miRNA profiling of cancer cells using SmartFlareTM, a novel live-cell RNA detection technology
Carmit Levy, PhD.
Principal investigator of Human Genetics & Biochemistry
Tel Aviv University-Sackler School of Medicine
Tel-Aviv, Israel 
Title: Role of microRNA-221 in melanoma

Daniela B. Munafo, PhD.
Applications and Product Development Scientist
New England Biolabs, Inc.
Ipswich, Massachusetts, USA
Title: Novel method for multiplex small--RNA library preparation with improved performance and higher sensitivity

Pavan Kumar, PhD.
Senior Scientist in Biomarkers Unit
Eisai, Inc.
Andover, MA, USA
Title: Current state of miRNAs as biomarkers

Marc Winnefeld, PhD.
Scientist, Research Division of Special Skincare
Beiersdorf AG
Hamburg, Germany
Title:: Identification of new targets involved in adipocyte differentiation by high throughput siRNA screening
John Doench, PhD. 
Research Scientist in RNAi Platform
The Broad Institute of MIT and Harvard
Boston, MA, USA
Title: Bugs into Features -- miRNA off-target effects in genome-wide RNAi screens

Timothy K. K. Kamanu, PhD.
Computational Bioscience Researcher
King Abdullah University of Science and Technology
Thuwal, Kingdom of Saudi Arabia
Title: Species-independent microRNA and microRNA gene discovery

Arati Sridharan , PhD.       
Researcher from Dr. J. Muthuswamy Lab
Biomedical Engineering
Arizona State University
Tempe, AZ, USA
Title: siRNA delivery using micro-electrode arrays

James Cardia, PhD.
Manager of Platform Technology
RXi Pharmaceuticals Corporation
Westborough, MA, USA
Title: Self-Delivering” RNAi Compounds for local delivery applications: From preclinical to clinical development

Dmitry Samarsky, Ph.D.
Executive Vice President
Technology Development
RiboBio Co., China
Title: RNAi and antisense oligonucleotide in vivo delivery for therapeutic applications

Kara A. Scheibner, PhD.                             
Assistant Professor in Pediatrics
University of Maryland School of Medicine
Center for Stem Cell Biology & Regenerative Medicine
Baltimore MD, USA
Title: Tumor suppressor microRNAs in acute leukemias

  Daniel Pregibon, PhD.                     
Firefly Bioworks, Inc.,
Cambridge, MA, USA
Title: Streamlined miRNA profiling for discovery and validation studies

Anne Dallas, PhD.
Senior Scientist
Somagenics Inc.
Santa Cruz, CA, USA
Title: Minimal-length synthetic shRNAs  (sshRNAs) have distinct and unusual Dicer-independent mechanisms of gene silencing



Exhibitors are welcome to reserve their booth space early!

Please contact if you are interested in speaking in the scientific or Technology workshops of this meeting.

GeneExpression Systems, Inc.
P.O. Box 540170
Waltham, MA 02454 USA
Tel: (781) 891-8181
Fax: (781)730-0700 or (781) 891-8234
E-mail: Genexpsys@expressgenes.com

Note: Speakers Names, Titles and venue subjected to change beyond our control for which the company is not responsible.

For Oral Presentation Abstracts Due By: Feb 31, 2013
For Poster Presentation Abstracts Due By: April 25, 2013

Email your abstract (100-200 words in word format) to: genexpsys@expressgenes.com

GeneExpression Systems™ All Rights Reserved 2013