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GeneExpression Systems, Inc & Appasani Research Conferences and Educational Institue (ARCEI.org)
Jontly Presents


Seventh International
Epigenomics, Sequencing & SNiPs-2014 Meeting

on ‘Chromatin Methylation to Disease Biology & Theranostics’

&
Second International
Metabolomics-2014 Symposium

on ' Diabetes, Obesity & Cardiovascular Diseases'


‘Insulin Resistance to Delivery, Body Weight Regulation & Devices’
‘Molecular Cardiology to Biotherapeutics & Stents’


Date: August 25 – 26, 2014

Venue: In Between Massachusetts Institute of Technology & Harvard University Campuses
on  777 Memorial Drive at Courtyard Marriott, Cambridge, Massachusetts 02139 USA


“A Unique Theme to Combine Chromatin biology, SNiPs and Diseases with Sequencing Chemistry”

Scope of the Meeting:

The purpose and scope of this 'Metabolomics Symposium' is to provide a forum for the discussion of the current state of the art in emerging branches of metabolic diseases that includes diabetes, obesity and cardiovascular diseases to develop appropriate biomarkers, therapeutics and devises for better diagnosis and treatment.

Metabolomics Symposium-2014 on ‘Diabetes, Obesity, Cardiovascular Diseases &Devices’will bring together young and established clinicians, researchers from  academia and industry (with diverse backgrounds in cardiology, cardiac surgery, endocrinology, diabetes, obesity research, stem cell biology, molecular/cellular biology, drug discovery and other aspects of metabolic disease biology), and discuss the clinical and drug/device discovery strategies in form of keynote lectures, invited talks, short oral, and poster presentations. Dedicated time allowed for presentation of posters, viewing the exhibits, to know the available cutting-edge reagent, devises and services in the field. The conference should be interesting for graduate students, postdoctoral fellows, professors, clinicians from academia and scientists, directors, chief scientific officers and chief executive officers from biopharmaindustry, as well as for anyone interested in studying cardiac and metabolic functions and their associated diseases. Authorities in the field selected and invited as presenting speakers.

Needless to say that Diabetes, Obesity and Cardio-vascular diseases are the major devastating metabolic syndromes in the westernized and developing world. This is the most important venue to bring together mix of quality presentations by high-caliber speakers and a place to exhibit lucrative medical devises. In this meeting we will bring latest innovations in the intersection of obesity, diabetes and cardiovascular diseases. Novel genome-wide, proteomics and systems biology approaches will be discussed to understand the molecular signaling events involved in diseased processes, and subsequently develop novel drug targets. This meeting will also highlight the cell therapy approaches using stem cells especially in the treatment of diabetes, vessel repair and regeneration. Most importantly, the latest devices and their applications in the delivery of insulin, glucose monitoring, vascular stents and synthetic valves will be discussed.

The venue is a cutting-edge conference facility located in Cambridge near the Harvard University Medical School nuclear campus (that consists of world-renowned teaching hospitals, Brigham & Women’s Hospital, Children’s Hospital, Beth Israel Deaconess Medical Center, Joslin Diabetes Center, Dana-Farber Cancer Institute, Harvard School of Public Health and close by Massachusetts General Hospital).

AGENDA

Expected Maximum Capacity:
Target Audience 200
Total Speaker Presentations: 30
Total Poster Presentations: 20
Total Exhibit Booths: 20


Monday, August 25, 2014
8:00 A.M: Registration Open
9.00 AM – 6.00 PM Scientific Sessions

Tuesday August 26, 2014
8:00 A.M: Registration Open
9.00 AM – 6.00 PM Scientific Sessions


The actual agenda will be updated


Scientific Organizer:

Krishnarao Appasani, PhD., MBA
Founder & CEO
GeneExpression Systems, Inc
Waltham, MA USA



Scientific Committee:
Laurie Jackson-Grusby, Ph.D.
Assistant Professor of Pathology
Children's Hospital
Harvard Medical School
Boston, MA USA
Alex Meissner, PhD.
Associate Professor of Stem Cell and Regenerative Biology
Harvard University &
Associate member of the Broad Institute
Cambridge, MA USA
Title:
DNA Methylation dynamics in stem cells and development


Key Seession:
Seventh International Second International
Epigenomics
on
Chromatin Methylation to Disease Biology & Theranostics

Diabetes, Obesity & CVD
on
Diabetes, Obesity & Cardiovascular Diseases

  • Mechanisms of Chromatin in gene regulation
  • Nuclear dynamics and Methylation Assays
  • Parental imprinting and Histone Deacetylation inhibitors as drugs
  • Epigenetic re-programming in stem cells
  • Cutting-edge sequencing technology; Epigenome Sequencing
  • Epigenetic regulatory processes in diseases & environment
  • Copy Number Variations & Genomo-wide Analysis
  • PharmacoEpigenomics
  • Biology of Diabetes, Obesity & Adipogenesis
  • Detection/Diagnosis using Biomarkers & Imaging
  • Insulin Resistance & Sugar Signaling Mechanisms
  • Novel Insulin Delivery Method
  • Genomic Studies of Complex Metabolic Diseases
  • Multiplex & High throughput Technology Platforms
  • Translational Medicine of Body Weight Regulation
  • Cardiovascular outcome in Diabetes & Obesity
  • Clinical, Etiological and Epidemiological Studies
  • Clinical Trials with Novel Anti-diabetic & Anti-obesity Drug Targets
  • Biology of Angiogenesis & Cardiac Diseases
  • Atherosclerosis, Valve Biology and Pathology
  • Molecular Orchestra of Cholesterol Metabolism
  • Detection/Diagnosis using Biomarkers & Imaging
  • Cardiome & Vascular Signaling Mechanisms
  • Genomics/Proteomics Technology Platforms
  • Translational Medicine of Metabolic Syndromes
  • Cardiovascular Repair, Regeneration & Cell Therapy
  • Coronary Intervention through Stents, Angioplasty & Novel Devices
  • Clinical Trials with Novel Drug Targets

Keynote Speaker:

Mark Gerstein, PhD.                        
Albert L. Williams Professor of Biomedical Informatics
Yale University
New Haven, CT, USA
Title: Human Genome Analysis


Other Speakers:

Epigenomics and Metabolomics
Pilar Blancafort, PhD.
Associate Professor & ARC Future Fellow
Group Leader, Harry Perkins Inst. for Med. Research
University of Western Australia
Crawley, WA, Australia
Title: Cancer epigenetics
Barry Merriman, PhD.
Lead Architect for Advanced Sequencing Technology
Thermo Fisher Scientific, Inc.
Carlsbad, CA, USA
Title: How to solve genetic disease on a population scale
Longzhi Tan, PhD, Student
Chemistry & Chemical Biology
Harvard University
Cambridge, MA, USA
Title: Rare event of histone demethylation can initiate singular gene expression of olfactory receptors
Trent Fowler, PhD.
Research Fellow in Pathology
Tufts University School of Medicine
Boston, MA, USA
Title:
Anticancer drug BRD4 inhibitor JQ1 

Paul D. Kaufman, PhD.
Professor in Molecular Medicine
University of Massachusetts Medical School
Worcester, MA, USA
Title:Regulation of nucleolar long-range interactions in human chromosomes

Aseel Eid, PhD. Student                                
College Of Pharmacy
University of Rhode Island
Kingston, RI, USA
Title: Epigenetic reprogramming in response to Lead (Pb) Exposure: Implications for Alzheimer’s disease
Subhrangsu S. Mandal, PhD.
Associate Professor of Chemistry & Biochemistry
The University of Texas at Arlington
Arlington, TX, USA
Title:
FHistone methylase MLL1 is associated with hypoxia signaling and angiogenesis, and tumorigenesis and is a novel target for cancer therapy

Miki Hieda, PhD.
Assistant Professorof Health Science
Osaka University-Graduate School of Medicine
Suita, Oasaka-fu,Japan
Title:  Cancer-associated aberrant histone modification promotes cell motility and invasion in several ways

Andrew A. Lane, MD, PhD.             
Instructor in Medicineat Harvard Medical School
Dana-Farber Cancer Institute
Boston, MA, USA
Title: Leukemogenesis and H3K27 hypomethylation driven by trisomy 21 and overexpression of HMGN1

Christopher M. Tracy, PhD.
Assistant Professorof Internal Medicine
Nora Eccles Harrison Cardiovascular Research Institute
University of Utah School of Medicine
Salt Lake City, UT, USA
Title: Chromatin proteome in cardiac hypertrophy

Jian Cao, PhD.
Associate Research Scientistof Pathology
Yale University School of Medicine
New Haven, CT, USA
Title: The function of histone demethylase RBP2 in breast cancer metastasis

Ronald Nick Laribee, PhD.
Assistant Professor of Pathology
University of Tennessee Health Science Center
Memphis, TN, USA
Title: mTORC1-dependent epigenetic regulation and the control of cell growth, proliferation and cell death responses

Sibaji Sarkar, PhD.
Instructor in Medicine
Boston University School of Medicine
Boston MA, USA
Title: Anticancer effects of HDA inhibitors

Gavin R. Schnitzler, PhD.
Assistant Professor of Medicine
Molecular Cardiology Research Institute
Tufts University Medical Center
Boston, MA, USA
Title:Mechanisms of vascular gene regulation by estrogen receptor alpha

Edyta Marcon, PhD.
Project Manager
Banting and Best Department of Medical Research
University of Toronto
Toronto, Canada
Title: Human interactome of chromatin-related factors and their roles in tumorigenesis

Ghazaleh Sadri-Vakili, PhD.
Assistant Professor of Neurology
Mass General Inst. for Neurodegenerative Disease
Charlestown, MA, USA
Title: Alterations in the Epigenome and Brain-Derived Neurotrophic Factor as a Mechanism of Transgenerational Inheritance in Response to Cocaine

Evan Daugharthy, PhD. Student
Department of Systems Biology
Harvard Medical School
Boston, MA, USA
Title: RNA Sequencing in-situ

Hao Anh Duong, PhD.
Research Fellow in Neurobiology
Harvard Medical School
Boston, MA, USA
Title:
Temporal orchestration of chromatin modifying enzymes in cyclic circadian gene expression

Benjamin G. Schroeder, PhD.
Senior Scientist 
NuGEN Technologies Inc.
San Carlos, CA, USA
Title: Improved Reduced Representation Bisulfite Sequencing on the Illumina Sequencing Platforms

Takeo Kubota, MD, PhD.
Professor of Epigenetics Medicine
University of Yamanashi School of Medicine &Engg.
Yamanashi, Japan
Title: Epigenetics as a basis for diagnosis and treatment of neurodevelopmental disorders

Mahua Choudhury, PhD.
Assistant Professorof Pharmaceutical Science
Texas A&M Health Science Center
Kingsville, TX, USA
Title: Phthalates- an invisible microRNA modulator in placenta

Julie Secombe, PhD.
Assistant Professorof Genetics
Albert Einstein College of Medicine
Bronx, NY, USA
Title: KDM5: More than just a demethylase

Bernhard Kuhn, MD.                                                                       
Assistant Professor of Pediatrics
Children’s Hospital of Boston &
Harvard Medical School
Boston MA, USA
Title: TBA

Zoltan Arany, MD., PhD.                                          
Associate Professor of Medicine
Cardiovascular Institute
Beth Israel Deaconess Medical Center
Harvard Medical SchoolBoston, MA, USA
Title:
TBA

Kami Ahmad, PhD.                                                              
Assistant Professorof Biological Chemistry
& Molecular Pharmacology
Harvard Medical School
Boston MA, USA
Title: Comprehensive profiling of regulatory elements in genomes

Jonathan Bogan, MD.
Associate Professor of Medicine
Yale University School of Medicine
New Haven, CT, USA
Title: A proteolytic pathway that regulates glucose uptake in fat and muscle
Michael Stitzel, PhD.
Assistant Professor
The Jackson Laboratory for Genomic Medicine
UConn Health Ctr. Campus, Farmington, CT, USA
Title: Epigenetics of islet dysfunction and type 2 diabetes

Nilanjana Banerjee, Ph.D.
Senior Research Staff Member
Clinical Informatics Solutions and Services
Philips Research North America
Briarcliff Manor NY, USA
Title: LncRNA and coding RNA interactions uncover novel transcriptomic effects of endocrine therapy in breast cancer

 

Exhibitors are welcome to reserve their booth space early!

Please contact if you are interested in speaking in the scientific or Technology workshops of this meeting.

GeneExpression Systems, Inc.
P.O. Box 540170
Waltham, MA 02454 USA
Tel: (781) 891-8181
Fax: (781)730-0700 or (781) 891-8234
E-mail: Genexpsys@expressgenes.com
www.expressgenes.com


Note: Speakers Names, Titles and venue subjected to change beyond our control for which the company is not responsible.

For Oral Presentation Abstracts Due By: July 20, 2014
For Poster Presentation Abstracts Due By: August 15, 2014

GeneExpression Systems™ All Rights Reserved 2014