Perspectives in Gene Expression
Front
Cover of the Book Back
of the Book
Introducing:
Perspectives in Gene Expression
Edited by: Krishnarao Appasani
Foreward by: Philip Sharp, Nobel Laureate, Institute Professor
at MIT
$135.00, pp 480 (est.), color insert
ISBN 1-881299-16-3
Perspectives in Gene Expression presents
gene expression strategies written by top scientists from
academic, biotechnology, and pharmaceutical institutes around
the world and provides a timeless collection of theory and
applications in various fields. Readers will find meaningful
interpretation and critical review of those aspects of the
molecular biology of disease that reflect on the role of
a cell’s genomic information.
Gene expression strategies covered
here include differential display, SAGE and real-time quantitative
PCR, cDNA microarrays, oligochips, and emerging technologies
such as RNAi and RAGE. These approaches offer a glimpse
into the potential for integrated healthcare and personalized
medicine.
(see reverse side for Table Of Contents)
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TABLE OF CONTENTS
Foreword
Introduction
SECTION I: DD-PCR
1. Discovery of Expressed
Genes by Differential Display and Their Applications
2. Identification of Genes in Leukemia Using Differential
Display
3. Gene Expression Studies in Lymphoid Cells Using Differential
Display
4. Gene Discovery in Experimental Colitis: mRNA Display
Approach
SECTION II:
SAGE and Validation
5. Genome-Wide Analysis
of Gene Expression in Human CD34+ Stem/Progenitor Cells
6. Expression of Novel Genes in Normal and Diseased Human
Tissues
SECTION III:
cDNA Arrays
7. Study of Mouse Metabolic
Pathways with RIKEN Full-Length cDNA Microarrays
8. Molecular Studies in Ovarian Cancer: A Tailored cDNA
Arrays Approach
9. Gene Expression Analysis of Ovarian Tumors with a cDNA
Microarray Containing Ovarian Tumor-Specific Clones
10. Microarray Applications in Developmental Toxicity
11. Identifying Antisense Genomic Modulators Using cDNA
Microarrays
SECTION IV:
Oligochips
12. Applicability and
Practice of Genome-Wide Expression Profiling: Insights from
Studies of Skeletal Muscle Diversity and Disease Mechanisms
13. Applications of Gene Expression Microarrays in the Discovery
of p53 Target Genes
14. The CodeLink Bioarray System Applied to Human Liver
Cancers
15. Expression Profiling in Helicobacter pylori Infection
SECTION V: Bioinformatics
16. Correspondence Analysis
with Microarray Data
17. High-Throughput Functional Interference in the Post-Genomic
Era
SECTION VI:
Emerging Technologies
18. Expression of siRNA
from a pol III Promoter in Mammalian Cells
19. Short Hairpin-Type dsDNAs Transcribed by pol III Polymerase
Induce Efficient Sequence-Specific Silencing in Human Cells
20. Inverse GenomicsÔ: A Gene Discovery Platform Based
on Inactivation of Gene Expression
21. Random Activation of Gene Expression (RAGE) Technology
22. Semiconductor Quantum Dots and Optically Encoded Microbeads
for Gene Expression Analysis
