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GeneExpression Systems, Inc & Appasani Research Conferences and Educational Institute (ARCEI.ORG)
Jointly Presents



Therapeutics Discovery Symposia USA - 2015

Two Theme Meetings at One Location

RNAi, MicroRNAs - 2015 Meeting
On
'RNA Interference, MicroRNAs: Biochemistry to Drugs &Therapeutics'

&
Stem Cells & Cell Signaling - 2015 Meeting
On
'Assays to Regenrative Medicine , Tissue Engineering & Therapeutics'

Date: MAY 4 – 5, 2015

Venue: In Between Massachusetts Institute of Technology & Harvard University Campuses
on  777 Memorial Drive at Courtyard Marriott, Cambridge, Massachusetts 02139 USA





Expected Maximum Capacity of each Meeting
Target Audience 100
Total Speaker Presentations: 30
Total Poster Presentations: 10
Total Exhibit Booths: 10


Click Here For Agenda


Monday, May 4, 2015
8:00 AM: Registration Open
9:00 AM - 6:30PM Scientific Sessions

Tuesday, May 5, 2015
8:00 A.M: Registration Open
9:00 AM - 3:30PM Scientific Sessions



SCOPE OF THE MEETING:

The purpose and scope of this Therapeutics Discovery Symposia USA - 2015 (on May 4-5, 2015) is to provide a forum for the discussion of the current state of the art of rapidly evolving RNA interference, MicroRNAs, Stem Cells and Regenerative Medicine highly interdisciplinary emerging fields in biotechnology. This will consists of two parallel theme meetings:

1.RNA interference & MicroRNAs-2015: This is our 12th international theme conference continuously held in the first week of May in Cambridge/Boston, Massachusetts, USA. Emeritus Professor Arthur Pardee of the Harvard University Medical School inaugurated our first meeting in May 2003. Since then, pioneers in both RNAi& MicroRNAs fields including: Nobel laureates Drs. Craig Mello, Richard Roberts and Professors Gary Ruvkun, David Bartel, Carlo Croce, and many more have given keynote speeches. RNAi and MicroRNAs are the “biology’s Big Bang” and we are igniting the spirit of both  RNomics&microRNomics in order to understand the biology of gene-silencing and to develop innovative products based on this technology platform.

2. Stem Cells & Cell Signaling-2015: This is our 8th international theme conference continuously held in either West Coast or East Coast of USA. Nobel Laureate Paul Berg of the Stanford University Medical School inaugurated our first meeting in 2006. Since then, pioneers in both Stem Cells & Tissue Engineering fields including: Nobel Laureate Elizabeth Blackburn, John Gurdon, and Professors Gail Martin, Irving Weissman, Ole Issacson, Helen Blau, Kevin Eggan and many more have given keynote speeches. Stem cells have great utility not only in cell biology and clinically for treatment of diseases, but also in drug discovery and development. Therefore, this meeting will focus on developmental aspects to signaling mechanisms and genome-scale mapping of DNA methylation in pluripotency as well highlights the stem cell based-therapeutics from biotech industry and associated novel reagent/assay/tool developments from reagent companies.

In this international meeting, prominent researchers (Developmental biologists, cell biologists, geneticists, molecular biologists, computational biologists, neurobiologists, clinicians, chemists and physicists)  from both academia and industry will gather and discuss the applications in form of keynote lectures, invited talks, short oral, and poster presentations.
These meetings are open for graduate students, postdoctoral fellows and professors from academia and research scientists and executives from bio-pharma industry to gain insights in the emerging frontiers in biotechnology.


Venue: Courtyard MARRIOTT is a star hotel located on the banks of Charles River in the close vicinity of world renowned Massachusetts Institute of Technology and Harvard University Campuses. This venue is minutes’ walk from theBiotech hub of University Park and Pharmaceutical giants such as: Novartis, Pfizer, Amgen and Takeda.

Note: All the members (except keynote speakers and others who arranged with organizer) who participate in this symposium have to register for the meeting by paying the appropriate registration fee


Scientific Organizer:

Krishnarao Appasani, PhD, MBA
Founder & CEO
GeneExpression Systems, Inc
Waltham, MA USA


Keynote Speakers:
Judy Lieberman, MD, PhD.             
Professor of Pediatrics
Children’s Hospital &Harvard Medical School
Boston MA, USA
Title: Knocking Down Disease: A Progress Report on siRNA therapeutics 
Derrick J. Rossi, PhD.                                 
Associate Professorof Stem Cell & Regenerative Biology
Harvard University&Harvard Stem Cell Institute
Boston MA, USA
Title: TBA


Other Speakers:

RNAi, MicroRNAs & Stem Cells Speakers:

 

Praveen Sethupathy, PhD.                         
Assistant Professorof Genetics
University of North Carolina
Chapel Hill, NC, USA
Title:Discovering candidate drivers of a stem cell-rich liver cancer, fibrolamellar carcinoma

Anthony K. L. Leung
Assistant Professor of Biochemistry
Johns Hopkins University
Baltimore, MD, USA
Title:Poly(ADP-ribose) regulation of microRNA activities

Daisy Robinton                                
PhD Candidate in George Daley’s Lab
Harvard University&Boston Children’s Hospital
Boston, MA, USA
Title:Lin28b is a compelling therapeutic target in hepatocellular carcinoma

Jim Barsoum, PhD.
Chief Scientific Officer
RaNA Therapeutics Inc.
Cambridge, MA, USA
Title: Selective activation of gene expression by targeting long noncoding RNA

Yvonne Tay, PhD.
National University of Singapore
Singapore
Title: MicroRNA and competing endogenous RNA networks in cancer

Anthony D. Kelleher, MBBS, PhD.
Professor of Immuno-Virology
St Vincent's Centre for Applied Medical Research &
University of New South Wales at Sydney
Darlinghurst, New South wales, Australia
Title: Transcriptional Silencing of HIV-1 through promoter targeted si/shRNA, induction of viral latency: an approach to stabilization of viral reservoirs

Rihab Nasr, PhD.
Associate Professor of Anatomy
Faculty of Medicine-American University of Beirut
Beirut, Lebanon
Title: MicroRNA expression profile analysis of Lebanese breast cancer tissues

Andrew Grimson, PhD
Assistant Professor of Molecular Biology
Cornell University
Ithaca, NY, USA
Title: Function of animal microRNAs and other small RNAs

Ying Tian, PhD
Assistant Professor of Pharmacology
The Center for Translational Medicine
Temple University School of Medicine
Philadelphia, PA, USA
Title:MicroRNA-Hippo pathway in cardiomyocyte proliferation and cardiac regeneration

Atish D. Choudhury, MD, PhD.
Instructor in Medicine&Medical Oncology
Dana-Farber Cancer Inst. & Harvard Medical School
Boston, MA, USA
Title: An in vivo genetic screen identifies NEK6 as a novel mediator of castration resistance in prostate cancer

Arun R. Shrivats, PhD.
Research Fellow
LifeNet Health
Virginia Beach, VA, USA
Title:RNAi Therapeutics for FibrodysplasiaOssificansProgressiva

Anna Kurzynska-Kokorniak                       
Institute of Bioorganic Chemistry PAS
Poznan, Poland
Title:Regulation of microRNA biogenesis by short RNA molecules

Shuling Guo, PhD.                           
Director, Antisense Drug Discovery
Isis Pharmaceuticals, Inc.
Carlsbad, CA, USA
Title:RNA-targeted therapeutic strategies using antisense technology

Pan Zheng, MD, PhD.
McKnew Professor for Cancer Biology
Children’s National Medical Center
Washington, DC, USA
Title:mTORC1 role in miRNA biogenesis

Amy K. Sater, PhD.                            
Professorof Biology and Biochemistry
University of Houston
Houston TX, USA
Title: Towards a Systems Analysis of miRNA - mRNA relationships in the establishment of vertebrate neural and epidermal lineages

Nicholas Delihas, PhD.                                           
Emeritus Professor of Molecular Genetics & Microbiology
Stony Brook University School of Medicine
Stony Brook, NY, USA
Title:Discovery and characterization of the first non-coding RNA gene, micF and its transcript that regulates gene expression-a historical perspective

  Laurence Ettwiller, PhD.                             
Research Scientist  
New England Biolabs, Inc.
Ipswich, MA, USA
Title:Enzymatic modification of the initiating nucleotide incorporated by the RNA polymerase identifies genome-wide transcription start sites in E. coli.
Suzanne Tharin, MD, PhD.
Assistant Professor of Surgery
Stanford University School of Medicine
Stanford, CA, USA
Title:microRNAs in corticospinal neuron development spinal cord injury

Khalid Shah, MS, PhD.                                            
Associate Professor of Radiology &Neurology
Mass. General Hospital&Harvard Medical School
Charlestown, MA, USA
Title: Engineering toxin-resistant therapeutics stem cells to treat brain tumors



* Presenting Speaker names, title and times are subject to change.
Host organization, organizer, or scientific committee does not take any kind of responsibility.


Key Topics:
RNAi, MicroRNAs & SCB-2015 Stem Cells -2015
  • The Genetics of RNAi and microRNAs
  • RNAi, Oligos delivery in vivo, in vitro
  • microRNAs and their diverse roles in biology & disease
  • Computational and Disease Biology of miRNAs
  • High throughput genome-wide screenings
  • Single cell qPCR in Stem cells, tumor cells
  • Fluorescence Spectroscopy & Correlation Microscopy
  • Single Molecule Genomics & Imaging in live cells
  • Atomic (Single Molecule) Force Microscopy
  • Fluorescent proteins and in vivo Analysis
  • Self-renewal and Maintenance
  • Stem Cells Propagation Techniques & Novel Reagents
  • Biopolymer Applications in Tissue Engineering
  • Epigenetic & Transcriptional Controls of Stem Cells
  • Signaling Mechanisms in Stem Cells
  • Tissue Organ Culture and Transplantation
  • Applications of Stem Cells to Human Diseases



Exhibitors are welcome to reserve their booth space early!

Please contact if you are interested in speaking in the scientific or Technology workshops of this meeting.

GeneExpression Systems, Inc.
P.O. Box 540170
Waltham, MA 02454 USA
Tel: (781) 891-8181
Fax: (781)730-0700 or (781) 891-8234
E-mail: Genexpsys@expressgenes.com
www.expressgenes.com


Note: Speakers Names, Titles and venue subjected to change beyond our control for which the company is not responsible.

Oral Presentation Submission by March 10, 2015
Poster Abstract Submission by April 20, 2015

Email your abstract (100-200 words in word format) to: genexpsys@expressgenes.com

GeneExpression Systems™ All Rights Reserved 2015